Database of mammalian genes
Home

Home Search Browse RAGs User guide FAQs Links Questions Contribute

Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for RAD23B (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID5887
Official gene symbolRAD23B
Full nameRAD23 homolog B (S. cerevisiae)
Aliases,HHR23B,HR23B,P58,
Gene summaryThe protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. This protein was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells. [provided by RefSeq]
LocationChromosome: 9   Locus: 9q31.2
Gene position110045544 - 110094470  Map Viewer
Gene orientationplus
Gene size48927 bp
Gene sequence
OMIM ID600062