Entrez gene ID | | 5887 |
Official gene symbol | | RAD23B |
Full name | | RAD23 homolog B (S. cerevisiae) |
Aliases | | ,HHR23B,HR23B,P58, |
Gene summary | | The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. This protein was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells. [provided by RefSeq] |
Location | | Chromosome: 9 Locus: 9q31.2 |
Gene position | | 110045544 - 110094470 Map Viewer |
Gene orientation | | plus |
Gene size | | 48927 bp |
Gene sequence |
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OMIM ID | | 600062 |
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