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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for RANBP1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID5902
Official gene symbolRANBP1
Full nameRAN binding protein 1
Aliases,HTF9A,MGC88701,
Gene summaryRan/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN. RANBP1 encodes a 23-kD protein that binds to RAN complexed with GTP but not GDP. RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP hydrolysis by the RanGTPase-activating protein (RanGAP1). The RANBP1 cDNA encodes a 201-amino acid protein that is 92% similar to its mouse homolog. In both mammalian cells and in yeast, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN. [provided by RefSeq]
LocationChromosome: 22   Locus: 22q11.21
Gene position20105024 - 20114704  Map Viewer
Gene orientationplus
Gene size9681 bp
Gene sequence
OMIM ID601180