Entrez gene ID | | 5922 |
Official gene symbol | | RASA2 |
Full name | | RAS p21 protein activator 2 |
Aliases | | ,GAP1M, |
Gene summary | | The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member has a perinuclear localization and is an inositol 1,3,4,5-tetrakisphosphate-binding protein; a compound suggested to function as a second messenger. [provided by RefSeq] |
Location | | Chromosome: 3 Locus: 3q22-q23 |
Gene position | | 141205926 - 141331197 Map Viewer |
Gene orientation | | plus |
Gene size | | 125272 bp |
Gene sequence |
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OMIM ID | | 601589 |
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