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Gene information for RASA2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID5922
Official gene symbolRASA2
Full nameRAS p21 protein activator 2
Aliases,GAP1M,
Gene summaryThe protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member has a perinuclear localization and is an inositol 1,3,4,5-tetrakisphosphate-binding protein; a compound suggested to function as a second messenger. [provided by RefSeq]
LocationChromosome: 3   Locus: 3q22-q23
Gene position141205926 - 141331197  Map Viewer
Gene orientationplus
Gene size125272 bp
Gene sequence
OMIM ID601589