Entrez gene ID | | 5927 |
Official gene symbol | | KDM5A |
Full name | | lysine (K)-specific demethylase 5A |
Aliases | | ,JARID1A,RBBP-2,RBBP2,RBP2, |
Gene summary | | The protein encoded by this gene is a ubiquitously expressed nuclear protein. It binds directly, with several other proteins, to retinoblastoma protein which regulates cell proliferation. This protein also interacts with rhombotin-2 which functions distinctly in erythropoiesis and in T-cell leukemogenesis. Rhombotin-2 is thought to either directly affect the activity of the encoded protein or may indirectly modulate the functions of the retinoblastoma protein by binding to this protein. [provided by RefSeq] |
Location | | Chromosome: 12 Locus: 12p11 |
Gene position | | 498620 - 389223 Map Viewer |
Gene orientation | | minus |
Gene size | | 109398 bp |
Gene sequence |
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OMIM ID | | 180202 |