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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for RBBP4 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID5928
Official gene symbolRBBP4
Full nameretinoblastoma binding protein 4
Aliases,NURF55,RBAP48,
Gene summaryThis gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. It is present in protein complexes involved in histone acetylation and chromatin assembly. It is part of the Mi-2 complex which has been implicated in chromatin remodeling and transcriptional repression associated with histone deacetylation. This encoded protein is also part of co-repressor complexes, which is an integral component of transcriptional silencing. It is found among several cellular proteins that bind directly to retinoblastoma protein to regulate cell proliferation. This protein also seems to be involved in transcriptional repression of E2F-responsive genes. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
LocationChromosome: 1   Locus: 1p35.1
Gene position33116749 - 33151812  Map Viewer
Gene orientationplus
Gene size35064 bp
Gene sequence
OMIM ID602923