Entrez gene ID | | 5931 |
Official gene symbol | | RBBP7 |
Full name | | retinoblastoma binding protein 7 |
Aliases | | ,MGC138867,MGC138868,RbAp46, |
Gene summary | | This protein is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that binds directly to retinoblastoma protein, which regulates cell proliferation. The encoded protein is found in many histone deacetylase complexes, including mSin3 co-repressor complex. It is also present in protein complexes involved in chromatin assembly. This protein can interact with BRCA1 tumor-suppressor gene and may have a role in the regulation of cell proliferation and differentiation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] |
Location | | Chromosome: X Locus: Xp22.2 |
Gene position | | 16888534 - 16862773 Map Viewer |
Gene orientation | | minus |
Gene size | | 25762 bp |
Gene sequence |
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OMIM ID | | 300825 |