Entrez gene ID | | 5981 |
Official gene symbol | | RFC1 |
Full name | | replication factor C (activator 1) 1, 145kDa |
Aliases | | ,A1,MGC51786,MHCBFB,PO-GA,RECC1,RFC,RFC140, |
Gene summary | | The protein encoded by this gene is the large subunit of replication factor C, which is a five subunit DNA polymerase accessory protein. Replication factor C is a DNA-dependent ATPase that is required for eukaryotic DNA replication and repair. The protein acts as an activator of DNA polymerases, binds to the 3' end of primers, and promotes coordinated synthesis of both strands. It also may have a role in telomere stability. [provided by RefSeq] |
Location | | Chromosome: 4 Locus: 4p14-p13 |
Gene position | | 39367995 - 39289076 Map Viewer |
Gene orientation | | minus |
Gene size | | 78920 bp |
Gene sequence |
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OMIM ID | | 102579 |
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