Entrez gene ID | | 599 |
Official gene symbol | | BCL2L2 |
Full name | | BCL2-like 2 |
Aliases | | ,BCL-W,BCLW,KIAA0271, |
Gene summary | | This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis. [provided by RefSeq] |
Location | | Chromosome: 14 Locus: 14q11.2-q12 |
Gene position | | 23776012 - 23780968 Map Viewer |
Gene orientation | | plus |
Gene size | | 4957 bp |
Gene sequence |
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OMIM ID | | 601931 |
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