| Entrez gene ID | | 5990 |
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| Official gene symbol | | RFX2 |
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| Full name | | regulatory factor X, 2 (influences HLA class II expression) |
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| Aliases | | ,FLJ14226, |
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| Gene summary | | This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. This protein can bind to cis elements in the promoter of the IL-5 receptor alpha gene. Two transcript variants encoding different isoforms have been described for this gene, and both variants utilize alternative polyadenylation sites. [provided by RefSeq] |
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| Location | | Chromosome: 19 Locus: 19p13.3-p13.2 |
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| Gene position | | 6110664 - 5993175 Map Viewer |
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| Gene orientation | | minus |
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| Gene size | | 117490 bp |
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| Gene sequence |
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| OMIM ID | | 142765 |
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