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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for RGS1 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 5996 Official gene symbol RGS1 Full name regulator of G-protein signaling 1 Aliases ,1R20,BL34,IER1,IR20, Gene summary This gene encodes a member of the regulator of G-protein signalling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signalling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. [provided by RefSeq] Location Chromosome: 1   Locus: 1q31 Gene position 192544857 - 192549159  Map Viewer Gene orientation plus Gene size 4303 bp Gene sequence >RGS1:44033499..44037801:Length=4303 GCCTGTCTGCATTCTACTATATAAAGCAGCAGAGACGTTGACTAGCGCATATTTGCTAAG AGCACCATGCGCGCAGCAGCCATCTCCACTCCAAAGTTAGACAAAATGCCAGGAATGTTC TTCTCTGCTAACCCAAAGGAATTGAAAGGAACCACTCATTCACTTCTAGACGACAAAATG CAAAAAAGGAGGCCAAAGACTTTGTAAGTTTGTTCAGAGTCTCACTTTGTGAATTTTAAC AAGTTATCTTTAATGGCAGAAGGATTGAGAATGAATGGAAGAGAGTGTGAGCATTTAGTT TAGCCAGATCAGAGGAGTTAATTGCCTGTTGTGAGTAATAAGTAATATTCAGCTGCATTA AAAAATAAATCTTGATATGGCATTAAATTGGGTAGGAGTTTTTCTCTACACAGGCTCATA AAAATGGGTTCTATAGCAAAATGTTGTATCAACCATTTTTAGTATTGCCTTATTCCTTAG AGAAATTTATTCTATGTCTTTTTACAAATAAAATGAATTCTGAAGAAATATGAATATTCA CTTTTATGTCTTTTGTAGTGGAATGGATATGAAAGCATACCTGAGATCTATGATCCCACA TCTGGAATCTGGAATGAAATCTTCCAAGTCCAAGGATGTGTAAGTACACTAATACACTAA ACTATCATTATCATTTACAAGAGAAGCCTATGCATTATCTCTATATCCCAGCAAGGGATA AATACTGCGCACAGTAGACTTCATTTCTTTTAAGTAACATGCCAAATAAAATTAGACTAT CAGTACCAATGTAAATTGAATACAAATGTGTACACACACATATTGGACTTTATCTATTTG GATTTTTTCAAATTTTATTGGCAGGTTTTTTTTTTCATAACTATAGTAACTCTAAGGGAA GTTTTGCATTTTGTGAATAAATTTTAACATATTTATTAGAACTACAGTTTCAGTTTGTGA AGTTATCAAAGTGTAACAGCCATTCTTATTTCATTTGTGCTTACATTTTAAAAATTGACT AATGTATGTACATTTTGTCCCCTGCAGACTTTCTGCTGCTGAAGTAATGCAATGGTCTCA ATCTCTGGAAAAACTTCTTGCCAACCAAAGTAAGTATAACTATTGAATGTTTCTGGGTTC AGCTAAATACTCTAAAAAATTGAATGGCTTCACTAAATATAGTATTCTGGGTAGGATAGT ATGCAAAAGGTTGTATTCTAGTTTGTCTGTAGTTACTGATAACTTCAGCATAGTATGCCT CTTAATAATGCTGACTTAGCACTCAATTCTGCCAACTCCTTTTAGACAAATTTGCCAAGA CAATTAGGTATTTTCATAGATCATTATGGAGATAAAATTAAACATTGTGCTGGGATTCTG ATATGTAAAAATTTTAAAAGTAAGCCAAATATTTTAATATGTACATTGCCATTTTGAAAT CTGCCTAAAGAATGTATTTTTCTACACTTGGATGTAACAAGTATGATTCATTCATTCAAT TAATTAAATTATCTTTCATACATTCATCATTCATCTCACCCTTATGTAGAGGACATTGTA GAGGTACCAAGGATTCAAAATCAAAGACAGTCTCTTACTGCCTTGAAGGTGGTTGAGATA CATAACATAAATAATTGCATTATTATAACATGATAGTTTTTATGACATAAATATGATAGA AGGATTTTTAAGCACATATAGTCTTGTGGAGATTTTCTGATGAGAGAAGGTAAAGAATGA AATCAGCTTGCCATCCCCTTGTCTTGGGCATTACAATTCTACTGAGATTAGGACCTTTTT CAGAGGTGTAGATGAGCAGTGTGGTCTCTATCTCTAAAGAGTGAGATTATTCTTTTCTCC CCACAGACACCCTAAGGAGCTTTACTTGGGAATCACATTGTTCACTCTAGCTCAGCTGAC TTTGTTTATAATTCAGCTAAACAAATAAATGGTATAGATATGGACCATAAATGGTGCCAT ATAAAAGTCTCAGTGAATGCTAGCAAACATAATTAGTACATCAGGCCTACAGATCATATA TAGGCCTAACATTTTCTGGCTAATATAAATTAGATGGGGAAATTATATTTACTAATTATT GTGATGTTAATGCCTTTTGTCAGTGTTTGCTTTCCTAAAATACTCTCTACTCTGGCTAAG ATTTGGCATATATAAAAGATGGTTTTATATTCAGTGGAGCAGAATTTCAATTCAAACCGC GGATAGAAGCAAAACAGTTTGGTAGCCACCATCAAGTAGCAATGTGACTATGAATGAGTT TGTCTGGCCCCAGATTCCTCTTCTATGAATGAAGAAATTTCAAATGACTTCTCATCTCTA CAATCTATAACACAGCTATTTCAGCAGTAGCTGTCTCTTACCTTTGTATGAATAGGAAGC AATTGTATTTTTCTTACAAATTTCTTCTTCAAATTATTCATTTGTTGGTTCATTTAATTT AATTATCTCCCCACCCACCCCTCGTTTCTTTTTAGCTGGTCAAAATGTCTTTGGAAGTTT CCTAAAGTCTGAATTCAGTGAGGAGAATATTGAGTTCTGGCTGGCTTGTGAAGACTATAA GAAAACAGAGTCTGATCTTTTGCCCTGTAAAGCAGAAGAGATATATAAAGCATTTGTGCA TTCAGATGCTGCTAAACAAGTGAGTATTAAGCTTATCATCATCAGTTTCTCCATAAAAGA CCCTATATGCAGAAATAACATTTAATATATACAACAAGATAAAATCCTTTTGGGGTATAT AATTTTACTTCTACATACTTAGGCATATAAATATAGTTCAGTGCAATGAGAATCTAATTT TCTATATTGGTGAGGGTTTCAGCACAGTAGAATAAAGAGACTGATTTTACAAAACCAGCT GCCATGATGAGGGTGAGGGAAGGGTTAAGGGTATTGTTACTGACCAGAACTGCATGTCAG GGAGTCCTTAATGAGTGCTCTTGTTTTGGATAAGAAAATGCAGATTAGCATAATGTATAC AATTGCAGCAGCAAAAGTATTTCCAATTAACAGTATTACCAGATAAATATTCTTGGTCCA AGCAGAAAATATCAACAAAAAGAGCCTTCTTCTCCTGTAAATCTTAAATGCCTACATCAC TCTTTATGATACATGGATCATCTTATGTGGATACTTAAATTTTTCATGTCTGCTTCTTTT GCCTCTCCTAACTATACTATGAGGAAATTTGGAACAAAGACATTTTTGTAATATTTCTTA TCTCCTTCACACCTAGTATAGAGCTGATTTTACAAAGGCATTTAAGAGATATTTGAATTG ATTTAAATGAGGCCTTAAAATTACTTTCTGAGGTGTTTCAAAAAACAGTAACATCATAAA ATTTGCAGTAAAGAAAAGTATATATTAGCTAACAAGGTTTTCTTTTTTAGATCAATATTG ACTTCCGCACTCGAGAATCTACAGCCAAGAAGATTAAAGCACCAACCCCCACGTGTTTTG ATGAAGCACAAAAAGTCATATATACTCTTATGGAAAAGGACTCTTATCCCAGGTTCCTCA AATCAGATATTTACTTAAATCTTCTAAATGACCTGCAGGCTAATAGCCTAAAGTGACTGG TCCCTGGCTGAAGGGAATTAACAGATAGTATCAAGCGCAGAAGGAATGTGCCAGTATGGC TCCCTGGGTGAACAGCTTGGCCTTTTTTGGGTGTCTTGACAGGCCAAGAAGAACAAATGA CTCAGAATGGATTAACATGAAAGTTATCCAGGCGCAGAGTTGAAGAAGCATAAGCAAGAC AAAAACAGAGAGACCGCAGAAGGAGGAAGATACTGTGGTACTGTCATAAAAAACAGTGGA GCTCTGTATTAGAAAGCCCCTCAGAACTGGGAAGGCCAGGTAACTCTAGTTACACAGAAA CTGTGACTAAAGTCTATGAAACTGATTACAACAGACTGTAAGAATCAAAGTCAACTGACA TCTATGCTACATATTATTATATAGTTTGTACTGAGCTATTGAAGTCCCATTAACTTAAAG TATATGTTTTCAAATTGCCATTGCTACTATTGCTTGTCGGTGTTATTTTATTTTATTGTT TTTGACTTTGGAAGAGATGAACTGTGTATTTAACTTAAGCTATTGCTCTTAAAACCAGGG AGTCAGAATATATTTGTAAGTTAAATCATTGGTGCTAATAATAAATGTGGATTTTGTATT AAAATATATAGAAGCAATTTCTGTTTACATGTCCTTGCTACTTTTAAAAACTTGCATTTA TTCCTCAGATTTTAAAAATAAATAAATAATTCATTTAAGATTC OMIM ID 600323