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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for RLN2 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 6019 Official gene symbol RLN2 Full name relaxin 2 Aliases ,H2,RLXH2,bA12D24.1.1,bA12D24.1.2, Gene summary Relaxins are known endocrine and autocrine/paracrine hormones, belonging to the insulin gene superfamily. In the human there are three non-allelic relaxin genes, RLN1, RLN2 and RLN3. RLN1 and RLN2 share high sequence homology. The active form of the encoded protein consists of an A chain and a B chain but their cleavage sites are not definitely described yet. Relaxin is produced by the ovary, and targets the mammalian reproductive system to ripen the cervix, elongate the pubic symphysis and inhibit uterine contraction. It may have additional roles in enhancing sperm motility, regulating blood pressure, controlling heart rate and releasing oxytocin and vasopressin. There are two alternatively spliced transcript variants encoding different isoforms described for this gene. [provided by RefSeq] Location Chromosome: 9   Locus: 9p24.1 Gene position 5304580 - 5299868  Map Viewer Gene orientation minus Gene size 4713 bp Gene sequence >RLN2:complement(5289868..5294580):Length=4713 ATGCCTCGCCTGTTTTTTTTCCACCTGCTAGGAGTCTGTTTACTACTGAACCAATTTTCC AGAGCAGTCGCGGACTCATGGATGGAGGAAGTTATTAAATTATGCGGCCGCGAATTAGTT CGCGCGCAGATTGCCATTTGCGGCATGAGCACCTGGAGCAAAAGGTCTCTGAGCCAGGAA GATGCTCCTCAGACACCTAGACCAGTGGCAGGTGAGAGCTCCCGCCCCCTCCCGGCCTTC CCGCGCTTCCCATTGGTTACTCTGGGGCGGCCGCCCAATTGGAACGGCGGCCTGCACGTC CGACTCGAGATCTCATTGGCTGCCACCGCTCAGCCCCTACTCAGCCGTGGCTGGTCCCTA AAGTTTGGGCTTTTCCTTTGCCAGGTGATTTTATTCAAACAGTCTCACTGGGAATCTCAC CGGACGGAGGGAAAGCACTGAGAACAGGAAGCTGCTTCACCCGAGAGTTCCTTGGTGCCC TTTCCGTAAGGCAGTCAGAGCGACGGGGTGGAAAGGGAGGGGAAGCCTCAGAGGAGGTGA CGCCGCCCGGAGACCCGCAGGAGGCCGGGCGCACTCCTGCACCCCACAGGAAAGCCAGGC GGCCAGACAGCGGGCGTGCTGGTGGGGGCACCTGAACAGGGCTTCTCGGATAGAGAGGAG AGGGGACAAACACTGAGGCGGCGCGCTAGTTATCAAGCCTGTTTGCGCGCCTGTAGGACG GGGCAACACTCTGAGGTCTCTGTGAGGGTCCCGTGATGGGAAGACAGGAAGGGCCTTACA CTTAATGACTCTCCTAGTCCAGAAGTTGGGCTGTGGCCTTTGCCATTGGAAACGTTCTTT AAAATAAACAAACAGAAAATCCCAAAGGAAAGAGTCTGACCTCCCGCTTCTTTGATCTGG GTATTGAAGTTCATTTGTGAGGCAGGGGATGGAAGAGAAAGGAAAGGCTTGAATGCCTTT AGGAGAAACTCAAGAGGACCAGAGACAAGGAAAGCAGGCCGTTCAGACCATCATAGCTGA AGACCCTACTGATGCTTTCAAGCATTTGGAAGCTGCAGTGGGTTTGCTTTAAAGGCAAGC TCTTAGAGTTGAGTACAGCTCAATCTGAAATGGCTTTTAAAAATATTTTAGTATTTATAA AGTAGCAGTGGAAACTCATGGAGGTATATACTAGTCTAAGAAGTGTAACGGGTCATATTA AATTCAGAGAAAGTAACCGCAGTTGCAAATACTAAGTGTTTTGTATTAGTATGACATGTA ATTTATGATAAACCGCAACTAAATTTTATAGGCTATATGCATATACTATATATAAATGAC TCTAACAGAAATACATTTACTTCTCTTTTATGAGATTTAAAGTATGCTTCTAAAGTTATT TACTTTTCTACATTGTTAGAGTTTGATTTATTTAATGGCAGTTTTTACATGACTTTTGTA TAACATTAGTACAAAAATACCACAACGTCTAGGAATTTAGTGATAAAAAGTAGAGAAGAC CGGATTGCATTGCATTTGCTTTATTATTCCACATTTTCTGACTATAAAAGTAGTAATGCT CATATTAAAGACAAATGTACATTAATGCAGCGTGAAAAATGAGAAGCACTCGTAGATATT AAGGACTTTGAAAAGTATATGTGAATTTTATGAGAAAATGAAATTATATTAAACAAGTAA GTGGAAAGAAATGTTAACATTTGGATAGGTATATGTATATATCTTTTGCATTTTCACTCA CCATTATACTTTGAGCAGTTTCTCACATTGTTATTATCCCAAAACACAATTTGAAATTCC TGTGTAGTATTTTTTGTCATAAATCTGCCACATACACTTAAGGATTCTTTGGTGGATATT TAGTTTATTTCTAAATTGTTGCTGAAAATACTTCATTAAGCACATTTGTATATAGATATG GCTACATTTTTATTTCCTTTGAAGAGACATGAGATTACAAAGTATTTTTAAAGAATTTTC TTTATTGATGTGCAGTATAATTTAACTGAAAGTAACCTCAGAAAATATTGCCTGCAGGTG GAGATTAAGACAAATGTTTACCATTACTAGGTAGGAATCGTTTTGGAAGTACATGTCAGT AATTTGTGATTAATTTGAGTTTTCAGACTTCTACTGTTAGGTAGTTGCTATTTGCTTCCA CATTATTACATTGTTAGCCATCCATTTCATCCTACAATATGTGCTAAAATCATATTCACT GCATCCCTTTTAAAAATAAGATACCCTTTAAACCAGAAGAGGCCTATTTTAGTGAGATTT ACATCCAAAATAATAAGTGAATAAGGGTATTTGTATGAATTCAGACAGAATATTTTCTTT GAGCCTAGGTTCCATAGCTAAAGGTGTTATGGATTATGAAATATTTCAAAACAGGTTTAA AAATATAATTTTAATAAAAGTATAAAATACACAGCCTATGAACAAACCTAATACAAACTA TAACTGTTTTGGCTGACTCATTTAACTGGCTTTAAGTATATAGAAAATTACCATCAGCTT CTTTCAGTATTTAATAAGGCCCCAACTACAGAAAGTTTAGGTTGGATCAAAGAGAGGTTT TTATGATGAAATTGAATTAAACTTAGGATGTCTTACTGAGGGGAAATGCCAAAACCTCTC ATTTAACCAAAAACGATATAAATTCTCATCTGTCATTTCCAGTTTAGAACATGAATGAGG GAGAGTGTTGGGAGGAAGGATGAAATACTACAGTTTGTTTTTTTTTATTCCTCTGTCAAA CTCCAATTGTTGAATTTTTTTGTTGGCTAGAAGGGGAACAACTGAATCTCTTGCCAGAAA ACTCAGGAAATGATCAGCCCCAGAACCACCGCTGTCTAGGTGAAGGGTCGTGGTTTCCTC TGATCAGCAGGCATCAGTGGTTAACCAGGTGTCTGCCTCCCGCACTTAGATTTACTCCCC TCTTCTCTTTATTTTCATTATTTCAAGAGTAATGCCTTGTTAATGGAGAGTTTTCCTGTC CAGGAAGAAGAGCAGCAAGACCTGATATGGGTTTTCACTGTAATTTAAACATCATCGTGT TTCTAATTTCTTTGTGAAATAAAACTATTAAGTTGTATAATTAGGACAGTTAAGGTTAGG AGAGGGTTTAACTCACTGTAAGCTTTTTGAGAGCAAGAAACATTTAAATAAATTTATATC TTTTAACTGGCAGTGCCAGAGACATGGAAACAGGTAATGAATGTTCAACTGAGCTGAATG GGTGCAAAGATGGAGGAAGATGTCAGCTGGGTGTCCAGCAGGTTCCCAGCCCAAGTCCCA GCCTTCACATTTGGCCAGCCTGGGATGCTGTGTAAGAACAGGCTCCCTTCCTAGGAGACA CACAGATCTTGCATAGTGCATGATCTGCAGCTTTGGAACAAATATCAAACAGAAAACATT AGTCAGTACACATACTCCACAGCAGATACAAATCTCTTCTTAAATCAGTGATTTTTGGTT AGTGTTCTTTTAACCCACTTCTCTCTTTCATATAAAATACTATTGTTTTGGAGTAAATAC TCTGGGGAAGACAAATTGTTAAATAGATGGTTAAGGAACATCAGAGACTTCTTTCTCCTG CTGATTAGATCAGAGGTGTTGGAAATTCTGCCTCTTTAACTTTATCCTCCAGGAGTAACT TCCCACCATGAAATATTCAATAGCTTAAAGTAATATCTTTTTCAAGGGTTACTATTACAA CTCATAATATCATAAATCATAGCAATGGAAGAAAATGACTTAACTAAGAAGAATCCAAGA AAATGACCACTAGCTGTGGTCAAACTGTTTTCAGTGACTTACATGACTTCAGAAAGATGA CAGATTAATGTCAGGGAGAGTCAAAAGTACTATGATAAAAGCACTGAGGGGATCATGAAG AGAGACGAGAGAGGACCAATGGGGTAAAGCAGAGCCTTGGTAAAATTATGGTACTTTAAG GTGTCCAACTGTAAGTAAGCTAAGTGTTTAGATATTAGGATGCTTGCTTATTTTGTTTCA ATGTTTAATTTATACTGAGGCAATGCTTTTTTGTCTATGCAAACATTCATAGTTTTTCTG AGTGCTCTTTGACATGAATATACCCTCACATACACCTTTTTTTTTAAATTTAACAGAAAT TGTGCCATCCTTCATCAACAAAGATACAGAAACCATAAATATGATGTCAGAATTTGTTGC TAATTTGCCACAGGAGCTGAAGTTAACCCTGTCTGAGATGCAGCCAGCATTACCACAGCT ACAACAACATGTACCTGTATTAAAAGATTCCAGTCTTCTCTTTGAAGAATTTAAGAAACT TATTCGCAATAGACAAAGTGAAGCCGCAGACAGCAGTCCTTCAGAATTAAAATACTTAGG CTTGGATACTCATTCTCGAAAAAAGAGACAACTCTACAGTGCATTGGCTAATAAATGTTG CCATGTTGGTTGTACCAAAAGATCTCTTGCTAGATTTTGCTGAGATGAAGCTAATTGTGC ACATCTCGTATAATATTCACACATATTCTTAATGACATTTCACTGATGCTTCTATCAGGT CCCATCAATTCTTAGAATATCTAAGAATCTTTGTTAGATATTAGGTCCCATCAATTCTTA GAATATCTAAACATCTTTGTTGATGTTTAGATTTTTTTATTTGATGTGTAAGAAAATGTT CTTTGTGTGATTAAATGACACATTTTTTTGCTG OMIM ID 179740