Entrez gene ID | | 602 |
Official gene symbol | | BCL3 |
Full name | | B-cell CLL/lymphoma 3 |
Aliases | | ,BCL4,D19S37, |
Gene summary | | This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B. [provided by RefSeq] |
Location | | Chromosome: 19 Locus: 19q13.1-q13.2 |
Gene position | | 45251978 - 45263301 Map Viewer |
Gene orientation | | plus |
Gene size | | 11324 bp |
Gene sequence |
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OMIM ID | | 109560 |
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