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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for RNF2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID6045
Official gene symbolRNF2
Full namering finger protein 2
Aliases,BAP-1,BAP1,DING,HIPI3,RING1B,RING2,
Gene summaryPolycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation. The protein encoded by this gene is one of the PcG proteins. It has been shown to interact with, and suppress the activity of, transcription factor CP2 (TFCP2/CP2). Studies of the mouse counterpart suggested the involvement of this gene in the specification of anterior-posterior axis, as well as in cell proliferation in early development. This protein was also found to interact with huntingtin interacting protein 2 (HIP2), an ubiquitin-conjugating enzyme, and possess ubiquitin ligase activity. [provided by RefSeq]
LocationChromosome: 1   Locus: 1q25.3
Gene position185014551 - 185071740  Map Viewer
Gene orientationplus
Gene size57190 bp
Gene sequence
OMIM ID608985