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Gene information for MRPS35 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID60488
Official gene symbolMRPS35
Full namemitochondrial ribosomal protein S35
Aliases,DKFZp762P093,HDCMD11P,MDS023,MGC104278,MRP-S28,MRPS28,
Gene summaryMammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that has had confusing nomenclature in the literature. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Pseudogenes corresponding to this gene are found on chromosomes 3p, 5q, and 10q. [provided by RefSeq]
LocationChromosome: 12   Locus: 12p11
Gene position27863706 - 27909237  Map Viewer
Gene orientationplus
Gene size45532 bp
Gene sequence
OMIM ID611995