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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for ROBO1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID6091
Official gene symbolROBO1
Full nameroundabout, axon guidance receptor, homolog 1 (Drosophila)
Aliases,DUTT1,FLJ21882,MGC131599,MGC133277,SAX3,
Gene summaryBilateral symmetric nervous systems have special midline structures that establish a partition between the two mirror image halves. Some axons project toward and across the midline in response to long-range chemoattractants emanating from the midline. The product of this gene is a member of the immunoglobulin gene superfamily and encodes an integral membrane protein that functions in axon guidance and neuronal precursor cell migration. This receptor is activated by SLIT-family proteins, resulting in a repulsive effect on glioma cell guidance in the developing brain. A related gene is located at an adjacent region on chromosome 3. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
LocationChromosome: 3   Locus: 3p12
Gene position79817059 - 78646388  Map Viewer
Gene orientationminus
Gene size1170672 bp
Gene sequence
OMIM ID602430