Home

Search

Browse

RAGs

User guide

FAQs

Links

Questions

Contribute

Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MRPL12 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 6182 Official gene symbol MRPL12 Full name mitochondrial ribosomal protein L12 Aliases ,5c5-2,FLJ60124,L12mt,MGC8610,MRP-L31/34,MRPL7,MRPL7/L12,RPML12, Gene summary Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein which forms homodimers. In prokaryotic ribosomes, two L7/L12 dimers and one L10 protein form the L8 protein complex. [provided by RefSeq] Location Chromosome: 17   Locus: 17q25 Gene position 79670407 - 79674548  Map Viewer Gene orientation plus Gene size 4142 bp Gene sequence >MRPL12:44944559..44948700:Length=4142 GCTCGAATGCCCGGCAGCCGTGGCGGCTAGAGCGTTCCTCCCCAGCTCGAATGCCCGGCG GCCGAGGCGGCTAGAGCGTCGCCTCCTCCCGGGGAACCGCGTGTGACCTTCCAGCCCGCG GACCGATGCTGCCGGCGGCCGCTCGCCCCCTGTGGGGGCCTTGCCTTGGGCTTCGGGCCG CTGCGTTCCGCCTTGCCAGGTACGCGGGATCCTGGGGCGGTCCGGGCCGGCAGGCGGGTT AGGGGGCAGCCGGGCACTGAGGGGTCGATCCGGGCGAGGAGGGCGGCGGGGCCGGCCTCC CTGCAGCGGCCAGGCCGGGCTTGGGGGTCCCATCGGGGGCGCGGGGAGGAGGCCTCCCGG TGCGCACGCCCCTTCCCTCCTGGGCCGTGGAAAGCGCCGGGGTCGGCCCCAGATGACCTT GGACGATTCCCTGCTCCTCCCTTGGCCTCAGCCTTTTCCGCAGCAAAGGCCCATCCGTGG GTGCGGCGTTTTGCGGCCAGGGGCCCCCATGTTTTGGGAGGCTTTGCGCAGGAAGATGCA CCTAAGTAATAGTTTCGCCACCGCTGGGTTGATGTAGTTCATTCAAACCAGAAACTTGAG GTTTGAGTGGTATGGCTGCAAATAAACACGTGGCTTTCTAAGGCTCTTTGAAGAATTTAA AGTAACTTGCAAATCTTATCAATACGGACCCCTTGAGGTCTGAGAACCCTGGACTGGGAC CAAGGAGCTAGGTAATTTCCGGCCCTAGTGATTACCAGCCTGAGCTTATGGCACCCACCA GTCCCCCAGTTGTCCTGCCCCTCTGGTTTCTGCAGCCCCTTCCATTCCAGGACTGACAAG TCTGTTTTAATTGGGGGTGGGGGCTAGGCGACAGGTGCCATGTGTCTGTGCCGTGCGACA TATGAGGAGCAGCGGCCATCAGAGGTGTGAGGCCCTCGCTGGTGCACCCCTGGATAACGC CCCCAAGGAGTACCCCCCCAAGATACAGCAGCTGGTCCAGGACATCGCCAGCCTCACTCT CTTGGAAATCTCAGACCTCAACGAGCTCCTGAAGGTATCGTGAGAGGGTGGCACAGACCC AGGGGCTGGAAGTTTCAGGGCCCCTGTGTTTTGTTCCTGGTGTATTTTGGGAGTTTGGTA AATTGTCAAAAGTGTGTTTGTCCAGGTGCAAGGTCCATGCCAGGCTAGTTGCCCCTCCTC AGTAGGTTCCGGCTGGTGTGAGGGCCAGCTGTGGACACTGTTCTCTATCTCTGCAGAAAA CGTTGAAGATCCAGGATGTCGGGCTTGTGCCGATGGGTGGTGTGATGTCTGGGGCTGTCC CTGCTGCAGCAGCCCAGGAGGTGAGTCCTGGGCAGAATGAGGCATTTCTGGGGTGCCCAG TTCGCCTGTGGCCTCATGTGCCGTGGTCCCGTATCTCAGGTTCTGCAGCTACCGTCATTG TCTGCAGCCTGCACACCTGTGCGGCATCCTGCAGCCTCCTGGGACCTACTCCCTGCCACG GATGTGCACGACTTTGCATGTGGAGACCATGTTTCTAATGGAGGGAAACAGACACTAAGC TGAGAGAGGAAAAAGAGGCTGGGCGTGGTGGCTCACGCCTGTAATCCCAGCGCTTCGGGA GGCCGAGACGGGTGGATCACTTGAGGTCAGGAGTTCGAGGCCAGCCTGGCCAACATGGTA AAACCCCGTCTCTACTAAAAATACAAAAAAAAAAAAATTAGCTGGGCCTGGTGGCACATG CCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATAGCTTGAACCCGGGAGACTG TCTCAAACAAACAAACAAAATAAATAAATAAAAATAAAAATAAATAAATAAATAAAAATA CAAAAATTAGCCGGCGTGGTGGCAGGTGCCTGTAATCCCAGCTACTTGGGAGGCTGAGGC AAGAGAATTGCTTGAACCAGGGAGGCGGAGGTTGCAGTGAGCCAAGATCATACTACTGCC TTCCAACTTGGCAACAGAGCAAGACCCTGTCTCAAAAAAAAAAAAAAAAAAAAAAGAGGA AAAAGAAAGGAAGAAATTATACCAAATAGAACATTGTAAGCATTGTGGGGAAAAGGAGGG AAGAGGCTCAAGGTGGGAGGGAGAGTTCCAAGTTCAAGGTGGGCTTCAAAGAGGAGGCAG ACATTGTAGAAGAGAGCACGGCCTTCCTGGCGGAGGACGGGGAGGCACCAAGGTCACCAG GCAAGAGGGTGTCTGACAATTCAGGGAGCAGCAGCGAGGTACAGGCTGGCGCAGGCGAAG GGGTGTAACAAGCAGCTCCGTCCTTGGGTCTTTGCAAGGAAACCAGTGAACTTGAAGCCG CCAGTTGCGTTTGGTCATCGGGTTGCGTGAACCTCTCCACCGGAGCCCTCCCCTCAGCCC CTTTCCCCCACTGGGGAACCAGGTTGTGTACTGTAGAGTGTCCCATGTTCCAGATGCGTG GGGTGCCCATGGGGCAGCATCACTCATGCCTGAGAACTGGAAGGTAGTTTAAAGGCTGAT TAGATTCAGGCCGAGCGTTTGGGTAAGAATAGCTGGGATTACTGTAGAGCCTGTTGTGTA AACTGGATTGCTTTTGAGGAGGGAGAAGATGTTATTAATAGCCTTCCCAGGCCGTGGGGA CACGCAGCCCCCTGCCCTCGGGTGGTGCTGGGTCTCCATGCGCCACGTCAGAAGCGCAGC GTGCCCGTCAGTCCCATGGCGGGTTGTCATTTTCTCGGCACACGTGCACTGCAGTGTGGC TGAGAAAGGAATGGCGCTGCTTTTATCTACAAAGCACTTTTGGTGTCGTTCTTTCCTGTC TCATAAGTTACGCTTTCTAAGCGAGAGGGGAGTAGAGTATTGAGGGAAGGACTGTGAAGC ATGTTTTTATTTATTTATGAAACCGAGTCTCACTCTGTCACCCAGGCTGGAGTGCAATGG CGCGATCTCAGCCCCCGCCTCCCGGGTTCAAGCAATTCTCATGCCGCAGCCTCCCGAGTA GCTGGGATTACAGGCGCGCACCACTAGAGACAGGGTTTCACCATATTGGTCAGGCTGGTT TCAAACTTGACCTCAAGTGATCCACCCGCCTTGGCCTCCCAAAGCGCTAGGATGACAGGC GTGAGCCACCGGAGCCACCACTCCCGTCCGAGGCATGTTACAAAGAGTTATTGGGCAGAC CTGCCTCTGACTAGCATGAGAGAAAAAGCACCAGCTGGACTCGCGAGGCCAAGGCAGGAG AATCGCTTGAACCCAGGAGGTGGAGGTTGCAGTGAGCTGAGGTCGCACCACTGCACTCCA GCCTGGATGACAGAGTGAGACTCCGTCTCAAAAAAAAGAGAAAAGAAAAGAAAAAGCACC AGCTGGTTAAGGATTGATGAGTTGGGAGACGTGACTTCCAACTCCAGGCTTCGCTGGGGC CTCCGCTGCACCTCCCTTTGGGGCTTTAGACTGGGGTGGCCCAGCAGTGGAGGCGTTAGC TCCCCCCAGCCCTTTGTCACCTGGCTCCCCTTCTTTCCTGCTCCCTAAGGCGGTGGAAGA AGATATCCCCATAGCGAAAGAACGGACACATTTCACCGTCCGCCTGACCGAGGCGAAGCC CGTGGACAAAGTGAAGCTGATCAAGGAAATCAAGAACTACATCCAAGGCATCAACCTCGT CCAGGTCTGTGCCGCGGTGGGGGTTCCGAGGCAGGTTCCGTTGTGGTGGCCAGGGCCCCC AGTCCCTGACTTTGCTCTCTCTGGCAGGCAAAGAAGCTGGTGGAGTCCCTGCCCCAGGAA ATCAAAGCCAATGTCGCCAAAGCTGAGGCGGAGAAGATCAAGGCGGCCCTGGAGGCGGTG GGCGGCACCGTGGTTCTGGAGTAGCCTCCAGCTCGGAGGACTTGTGTTCAGGGGTCCTGG GCCCCGGGCGAGGTCCCGCCCTCCCGTGGTCACTGGCTCCGCCCCCAGCACCAGGCGCCC AGTGGAGCCGTTTGGGAGAATTGCCTGCGCCACGCAGCGGGGCCGGACAGGCCGCACAGA CCTACTGTGGCGGGAGGGAGGGGCGGCTGCTGCCTGGTGACGGCACCCGGAGGCCCACCA GGACGCGCCACCGGTGAATGTGCCTCTGGTGGCTGCTGAGAAAAATACACTGTGCAGCTC AG OMIM ID 602375