Entrez gene ID | | 6197 |
Official gene symbol | | RPS6KA3 |
Full name | | ribosomal protein S6 kinase, 90kDa, polypeptide 3 |
Aliases | | ,CLS,HU-3,ISPK-1,MAPKAPK1B,MRX19,RSK,RSK2,S6K-alpha3,p90-RSK2,pp90RSK2, |
Gene summary | | This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Mutations in this gene have been associated with Coffin-Lowry syndrome (CLS). [provided by RefSeq] |
Location | | Chromosome: X Locus: Xp22.2-p22.1 |
Gene position | | 20284750 - 20168029 Map Viewer |
Gene orientation | | minus |
Gene size | | 116722 bp |
Gene sequence |
| |
OMIM ID | | 300075 |
|