Entrez gene ID | | 622 |
Official gene symbol | | BDH1 |
Full name | | 3-hydroxybutyrate dehydrogenase, type 1 |
Aliases | | ,BDH,MGC2723,MGC4347,MGC9788,SDR9C1, |
Gene summary | | This gene encodes a member of the short-chain dehydrogenase/reductase gene family. The encoded protein forms a homotetrameric lipid-requiring enzyme of the mitochondrial membrane and has a specific requirement for phosphatidylcholine for optimal enzymatic activity. The encoded protein catalyzes the interconversion of acetoacetate and (R)-3-hydroxybutyrate, the two major ketone bodies produced during fatty acid catabolism. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq] |
Location | | Chromosome: 3 Locus: 3q29 |
Gene position | | 197300194 - 197236654 Map Viewer |
Gene orientation | | minus |
Gene size | | 63541 bp |
Gene sequence |
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OMIM ID | | 603063 |