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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for RPS27A (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 6233 Official gene symbol RPS27A Full name ribosomal protein S27a Aliases ,CEP80,UBA80,UBCEP1,UBCEP80, Gene summary Ubiquitin, a highly conserved protein that has a major role in targeting cellular proteins for degradation by the 26S proteosome, is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin fused to an unrelated protein. This gene encodes a fusion protein consisting of ubiquitin at the N terminus and ribosomal protein S27a at the C terminus. When expressed in yeast, the protein is post-translationally processed, generating free ubiquitin monomer and ribosomal protein S27a. Ribosomal protein S27a is a component of the 40S subunit of the ribosome and belongs to the S27AE family of ribosomal proteins. It contains C4-type zinc finger domains and is located in the cytoplasm. Pseudogenes derived from this gene are present in the genome. As with ribosomal protein S27a, ribosomal protein L40 is also synthesized as a fusion protein with ubiquitin; similarly, ribosomal protein S30 is synthesized as a fusion protein with the ubiquitin-like protein fubi. Multiple alternatively spliced transcript variants that encode the same proteins have been identified.[provided by RefSeq] Location Chromosome: 2   Locus: 2p16 Gene position 55459039 - 55462989  Map Viewer Gene orientation plus Gene size 3951 bp Gene sequence >RPS27A:34280926..34284876:Length=3951 AAGACCCAGACTCTTCCCTAGGCTGGGAGAGACTCGGCGGTTGAAAGCAGGGAGGCGCTA CAGGAGAGAAAGGGCTGAACCCCCGCTTCCGCAGATTTCACCTATTTTTCAGTTTGCCTG GAGCAGGCCACGCAAATTCCCTTCCCTTGAAGGCCCAAGGAGCGTCTGGTAGATTGCTGA TTCTCTGCCCATCACCGCTTCTGGAAGTGAGTGAAGGACACCTTTCGTGCCCCGCACCCT TTGCCCCCCGCTTAACATTTGCTCTAGTCACTTCCGGCCCGTTCCCACGCTCCGGAAACC ATTATTCCGCTTCATCCTACCTCCAGTCCTCACCTGAGTCCTTTTCTCCAAACACCGACT TCAGTGCTTAGAGATAGTAACTAGGGAATCTGGGAGGTGGAACTGCATCTTGGGACAAGT AGTCCAAGGTAGAAGAAAGCAGTGGAGAACTACAGTTCCCAGAATGCACTTCCATTTCCT ACCTCTTCCCCAAGAGGCCCCCCTCGACCTCCTTTTAAAAATTCTCTTAGCCACGTTGAT TGTACGGGAAAAGCCTTTTTAAAACATCTTTTACGTTGCTTAAACCTACAGTTTCGAAAG CATTCCGAAGGCTAAAGTGAGAAATAAGCCCAGGCTAGGGAGAGGAGAAACGAAGTTCAC GTCCTAGTCTGGCACCGGGTTGGATTGTCGCTGGGACGGCAGTCAGGCATTTGGTGTGGT CGCCTAAGGGGTGGGTCCTTCGGCGGGAGCTCCGGGAAACCCCGTGGGCCTGCGCGGCGT TCTTCCTTTTCGATCCGCCATCTGCGGTGGGTGTCTGCACTTCGGCTGCTCTCGGGTTAG CACCCTATGGTGCCTTCTCTTGTGATCCCTGACCTAACCTGTCTCTTCCTTTTCCTCAAC CTCAGGTGGAGCCGCCACCAAAATGCAGATTTTCGTGAAAACCCTTACGGGGAAGACCAT CACCCTCGAGGTACGGGCCGGGTGGTCATGAGGAAGCCAAGGTCCGAATAAGGTCCTGAG GTGGATTTTAGGACCGGCGCTGCTTTCCATGTCTTAGACCATGATTCCGAATTTGGGTTC TAAAACTTAAGCTTTGAAATGAGTACCTTTTGCTGAGCAACGACCTAGAGGTGATTTTCG GTGGCCAAAGGCTGGACCTGTCTCCTCTCGAGGGGTTCCAGCTAGTTAGTTAAAACGGAG GAGCTGCGGTGGGGAAGGAGACGCTCTGCCCGCCGGGTGCGAGCACGTGTGGCCCTGCGG CCGCCGCCCGCTCTGGGCTGGGGAGATGAAGGTGCTTTCCGGTAGCCGACTTGGGAGGTT GCCCACTGGGTGGGTAATAGGTCTCTCGAGTAGGTCTCAGCCCTGTCGCTGGTTCGGTTC AGTGGTAATTGTCAAACTAAATGAGTTCTGCTGTAGTTCCTTAATGTGTAACCAACATGC TTTCACTTTAACACTCATAGGTTGAACCCTCGGATACGATAGAAAATGTAAAGGCCAAGA TCCAGGATAAGGAAGGCAAGTAGTATTTTGTAGTTAAGAAAACTTAACCTGCGGAGACTT CGGCCTACCTGTAGGTGCTAGACATACCTGCTCTTGGTGATGGGGGAAGGGGTCAGATTG ACAAAGCGAAATACTTGTGGAATAACACAATAGACATTGGTGATCGGGGAGCACAGTACC TAGATTGGAATCCTTGAGGTGTATTTCACTTGCGTGAATTTGGACACTTATTTATTTATT TTGTGTGAGATGGAGTCTCCTCTGTCGCCCAGGCTGGAGTGCATTCGCTTGTCCCGGCTT ACTGCAGCCTCCGCCTCCCGGGTTCAAGTGATTTTTGTGCTTCAGCCTCCCTATTAGTGG GGATTACAGGCGTGCACCACCATGCCTGGCTAATTTATTGTATTTTTAGTAGAGACTGGG TTTTACCTTGTTGGCCAGGCTGGTTTTGAACTTTTCACATCAAGTGATCTGCCCACCTCG ACCTCCCAAAGTATTGGTATTACAGGTGTCAGCCACTGCAGACAACCAAGTATTGTCCCT AATATTAAATGCGGTAAAATGTGACATGTAAAGATTTAGAACCATGCCTAACCTCTAGTA AGGGCTTATTGTCAGCCTTTAGTATCATGTATTTGATTAAGGGGTGTTACCTTATAAGTC TGGAGCACATCACAGGCTTGGTGTGCTGTGACTTAATTTTTGTTTTTTGTCATTAGGAAT TCCTCCTGATCAGCAGAGACTGATCTTTGCTGGCAAGCAGCTGGAAGATGGACGTACTTT GTCTGACTACAATATTCAAAAGGTCTGTCTAGGGGAAGAGCAGCCTCTTTTAAAAAAAAA ATGTTATTTTGGAAATTTTTTATTTTACTTTTTTTGAGACAGGCTCTGACTCTGTCACCT AGGGTGGAGTGAGTGGCGCAGTCACTGCAACCTCCACCTCTCAGACTCAGGTGGTCCTCC CACCTCAGCCTCCTGTAGTTGGAACTATAGGCACCCGCCACCATGCCCAGGCTGGTCTCA AACTCCTGGGCATAAGTGATCTTCCCACCGTGGCCTCCCAGCGCTGGGATTACAGACGTG AGCCACTCCATGTGGTGTATTCTGGACATTTTGACACACAAAAAGGGAAAATGGCATTCG AATAGCAGTAGATTTTTAGGTAACTCCTATACTGATACTTGAGAAGCACTGCTATAGTTC TCCCATTATGAATTTTGCAAGTTGTATCCCATGGTGTAATGTAATGCATTCTTTAATGTC CCTATAAACTGTCAGTTAAGAATCTGATACTTTATTGGGTTTGGGGGCTGCAAGATTCCC TCAAATGTTATTGTGTGCTGCTACTGCTTTTAATTAGAAAATGCATAATGTTGGGTGTGC CCATTCTTAGTGGAATCATGAAAGCTTGCTTCATTCTTCCATTAACAGGAGTCTACTCTT CATCTTGTGTTGAGACTTCGTGGTGGTGCTAAGAAAAGGAAGAAGAAGTCTTACACCACT CCCAAGAAGAATAAGCACAAGAGAAAGAAGGTTAAGCTGGCTGTCCTGAAATATTATAAG GTGAGCCAGTTAAAGGGCAGAATGTCAGCAAAGTCTTGGCTTATTTGGAAAACTTAATCT TTATAGTACTTGTCAATATTTTCTTGGACTTAAACACCCAATATTATCCCACTTTGGTTT AAATGAGGTATTCTGGAAATGAGAAATTCAGACTTTCTGGGGTTTTTCCTGTTTGGTATT TGAAATCAGTTATGTAATAGGGTTCTGAGTTTAAAGTCGGGTTTGGGTTCAGGTCTTTAC CTTTGTCTACCACTTGCAAAGCTGGCCTTTAGTGTTCAAAAGTCCCAAGACTTCTGAATG TTTTCATTGTAGCAATGATAACTGGTGAGAATTTAGGGTGCTTTGGTTTGTAAGCACCAA AACCACCAGTATTACACAGTTAAAAGCTTAAATATTTTGAGTCACTTAAATTAGACTTCA GAATGTGTTGTAAAATTATCTTAACAGCAGGTTTGTGCTTTTCAGGTGGATGAGAATGGC AAAATTAGTCGCCTTCGTCGAGAGTGCCCTTCTGATGAATGTGGTGCTGGGGTGTTTATG GCAAGTCACTTTGACAGACATTATTGTGGCAAATGTTGTCTGACTTACTGTTTCAACAAA CCAGAAGACAAGTAACTGTATGAGTTAATAAAAGACATGAACTAACATTTATTGTTGGGT TTTATTGCAGTAAAAAGAATGGTTTTTAAGCACCAAATTGATGGTCACACCATTTCCTTT TAGTAGTGCTACTGCTATCGCTGTGTGAATGTTGCCTCTGGGGATTATGTGACCCAGTGG TTCTGTATACCTGCCAGGTGCCAACCACTTGTAAAGGTCTTGATATTTTCAATTCTTAGA CTACCTATACTTTGGCAGAAGTTATATTTAATGTAAGTTGTCTAAATATAA OMIM ID 191343