Entrez gene ID | | 6278 |
Official gene symbol | | S100A7 |
Full name | | S100 calcium binding protein A7 |
Aliases | | ,PSOR1,S100A7c, |
Gene summary | | The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein differs from the other S100 proteins of known structure in its lack of calcium binding ability in one EF-hand at the N-terminus. This protein is markedly over-expressed in the skin lesions of psoriatic patients, but is excluded as a candidate gene for familial psoriasis susceptibility. The exact function of this protein is not known. [provided by RefSeq] |
Location | | Chromosome: 1 Locus: 1q21 |
Gene position | | 153433137 - 153430220 Map Viewer |
Gene orientation | | minus |
Gene size | | 2918 bp |
Gene sequence |
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OMIM ID | | 600353 |
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