Entrez gene ID | | 6386 |
Official gene symbol | | SDCBP |
Full name | | syndecan binding protein (syntenin) |
Aliases | | ,MDA-9,ST1,SYCL,TACIP18, |
Gene summary | | The protein encoded by this gene was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic, C-terminal domains of a variety of transmembrane proteins. This protein may also affect cytoskeletal-membrane organization, cell adhesion, protein trafficking, and the activation of transcription factors. The protein is primarily localized to membrane-associated adherens junctions and focal adhesions but is also found at the endoplasmic reticulum and nucleus. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq] |
Location | | Chromosome: 8 Locus: 8q12 |
Gene position | | 59465728 - 59495419 Map Viewer |
Gene orientation | | plus |
Gene size | | 29692 bp |
Gene sequence |
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OMIM ID | | 602217 |
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