Entrez gene ID | | 6387 |
Official gene symbol | | CXCL12 |
Full name | | chemokine (C-X-C motif) ligand 12 |
Aliases | | ,IRH,PBSF,SCYB12,SDF1,SDF1A,SDF1B,TLSF,TPAR1, |
Gene summary | | This gene encodes a stromal cell-derived alpha chemokine member of the intercrine family. This gene product and its receptor CXCR4 can activate lymphocytes and have been implicated in the metastasis of some cancers such as breast cancer. Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections. Multiple transcript variants encoding different isoforms have been found for this gene. |
Location | | Chromosome: 10 Locus: 10q11.1 |
Gene position | | 44880545 - 44865605 Map Viewer |
Gene orientation | | minus |
Gene size | | 14941 bp |
Gene sequence |
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OMIM ID | | 600835 |