Entrez gene ID | | 63931 |
Official gene symbol | | MRPS14 |
Full name | | mitochondrial ribosomal protein S14 |
Aliases | | ,DJ262D12.2,HSMRPS14,MRP-S14, |
Gene summary | | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S14P family. Alternative splicing results in multiple transcript variants. [provided by RefSeq] |
Location | | Chromosome: 1 Locus: 1q23-q25 |
Gene position | | 174992561 - 174983128 Map Viewer |
Gene orientation | | minus |
Gene size | | 9434 bp |
Gene sequence |
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OMIM ID | | 611978 |