| Entrez gene ID | | 6453 |
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| Official gene symbol | | ITSN1 |
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| Full name | | intersectin 1 (SH3 domain protein) |
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| Aliases | | ,ITSN,MGC134948,MGC134949,SH3D1A,SH3P17, |
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| Gene summary | | The protein encoded by this gene is a cytoplasmic membrane-associated protein that indirectly coordinates endocytic membrane traffic with the actin assembly machinery. In addition, the encoded protein may regulate the formation of clathrin-coated vesicles and could be involved in synaptic vesicle recycling. This protein has been shown to interact with dynamin, CDC42, SNAP23, SNAP25, SPIN90, EPS15, EPN1, EPN2, and STN2. Multiple transcript variants encoding different isoforms have been found for this gene, but the full-length nature of only two of them have been characterized so far. [provided by RefSeq] |
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| Location | | Chromosome: 21 Locus: 21q22.1-q22.2 |
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| Gene position | | 35014784 - 35261609 Map Viewer |
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| Gene orientation | | plus |
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| Gene size | | 246826 bp |
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| Gene sequence |
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| OMIM ID | | 602442 |
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