Entrez gene ID | | 64663 |
Official gene symbol | | SPANXC |
Full name | | SPANX family, member C |
Aliases | | ,C,CT11.3,CTp11,SPANX-C, |
Gene summary | | Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family, which is located in a gene cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular gene encodes a protein that localizes to the nucleus and is expressed in highly metastatic cell lines, making the protein a potential diagnostic and prognostic marker. The protein belongs to a family of cancer/testis antigens and represents a potential target for cancer immunotherapy. [provided by RefSeq] |
Location | | Chromosome: X Locus: Xq27.1 |
Gene position | | 140336646 - 140335596 Map Viewer |
Gene orientation | | minus |
Gene size | | 1051 bp |
Gene sequence |
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OMIM ID | | 300330 |
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