Entrez gene ID | | 6494 |
Official gene symbol | | SIPA1 |
Full name | | signal-induced proliferation-associated 1 |
Aliases | | ,MGC102688,MGC17037,SPA1, |
Gene summary | | The product of this gene is a mitogen induced GTPase activating protein (GAP). It exhibits a specific GAP activity for Ras-related regulatory proteins Rap1 and Rap2, but not for Ran or other small GTPases. This protein may also hamper mitogen-induced cell cycle progression when abnormally or prematurely expressed. It is localized to the perinuclear region. Two alternatively spliced variants encoding the same isoform have been characterized to date. [provided by RefSeq] |
Location | | Chromosome: 11 Locus: 11q13 |
Gene position | | 65405578 - 65418391 Map Viewer |
Gene orientation | | plus |
Gene size | | 12814 bp |
Gene sequence |
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OMIM ID | | 602180 |