Entrez gene ID | | 64968 |
Official gene symbol | | MRPS6 |
Full name | | mitochondrial ribosomal protein S6 |
Aliases | | ,C21orf101,MRP-S6,RPMS6,S6mt, |
Gene summary | | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S6P family. Pseudogenes corresponding to this gene are found on chromosomes 1p and 12q. [provided by RefSeq] |
Location | | Chromosome: 21 Locus: 21q21.3-q22.1 |
Gene position | | 35445823 - 35515334 Map Viewer |
Gene orientation | | plus |
Gene size | | 69512 bp |
Gene sequence |
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OMIM ID | | 611973 |