Entrez gene ID | | 64969 |
Official gene symbol | | MRPS5 |
Full name | | mitochondrial ribosomal protein S5 |
Aliases | | ,MRP-S5,S5mt, |
Gene summary | | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S5P family. Pseudogenes corresponding to this gene are found on chromosomes 4q, 5q, and 18q. [provided by RefSeq] |
Location | | Chromosome: 2 Locus: 2p11.2-q11.2 |
Gene position | | 95787754 - 95752952 Map Viewer |
Gene orientation | | minus |
Gene size | | 34803 bp |
Gene sequence |
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OMIM ID | | 611972 |
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