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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MRPL11 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID65003
Official gene symbolMRPL11
Full namemitochondrial ribosomal protein L11
Aliases,CGI-113,L11MT,MGC111024,MRP-L11,
Gene summaryMammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Sequence analysis identified three transcript variants that encode different isoforms. Pseudogenes corresponding to this gene are found on chromosomes 5q and 12q. [provided by RefSeq]
LocationChromosome: 11   Locus: 11q13.3
Gene position66206310 - 66202550  Map Viewer
Gene orientationminus
Gene size3761 bp
Gene sequence
OMIM ID611826