Entrez gene ID | | 6530 |
Official gene symbol | | SLC6A2 |
Full name | | solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2 |
Aliases | | ,NAT1,NET,NET1,SLC6A5, |
Gene summary | | This gene encodes a member of the sodium:neurotransmitter symporter family. This member is a multi-pass membrane protein, which is responsible for reuptake of norepinephrine into presynaptic nerve terminals and is a regulator of norepinephrine homeostasis. Mutations in this gene cause orthostatic intolerance, a syndrome characterized by lightheadedness, fatigue, altered mentation and syncope. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene. |
Location | | Chromosome: 16 Locus: 16q12.2 |
Gene position | | 55689542 - 55740104 Map Viewer |
Gene orientation | | plus |
Gene size | | 50563 bp |
Gene sequence |
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OMIM ID | | 163970 |
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