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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for BMPR1A (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID657
Official gene symbolBMPR1A
Full namebone morphogenetic protein receptor, type IA
Aliases,10q23del,ACVRLK3,ALK3,CD292,SKR5,
Gene summaryThe bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. [provided by RefSeq]
LocationChromosome: 10   Locus: 10q22.3
Gene position88516396 - 88684945  Map Viewer
Gene orientationplus
Gene size168550 bp
Gene sequence
OMIM ID601299