Entrez gene ID | | 65993 |
Official gene symbol | | MRPS34 |
Full name | | mitochondrial ribosomal protein S34 |
Aliases | | ,MGC2616,MRP-S12,MRP-S34,MRPS12, |
Gene summary | | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. Alternate splice variants of this gene have been described but their full-length nature has not been determined. [provided by RefSeq] |
Location | | Chromosome: 16 Locus: 16p13.3 |
Gene position | | 1823140 - 1821896 Map Viewer |
Gene orientation | | minus |
Gene size | | 1245 bp |
Gene sequence |
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OMIM ID | | 611994 |