Entrez gene ID | | 664 |
Official gene symbol | | BNIP3 |
Full name | | BCL2/adenovirus E1B 19kDa interacting protein 3 |
Aliases | | ,NIP3, |
Gene summary | | This gene is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein which is responsible for the protection of virally-induced cell death, as well as E1B 19 kDa-like sequences of BCL2, also an apoptotic protector. This gene contains a BH3 domain and a transmembrane domain, which have been associated with pro-apoptotic function. The dimeric mitochondrial protein encoded by this gene is known to induce apoptosis, even in the presence of BCL2. [provided by RefSeq] |
Location | | Chromosome: 10 Locus: 10q26.3 |
Gene position | | 133795435 - 133781204 Map Viewer |
Gene orientation | | minus |
Gene size | | 14232 bp |
Gene sequence |
| |
OMIM ID | | 603293 |
|