Entrez gene ID | | 6642 |
Official gene symbol | | SNX1 |
Full name | | sorting nexin 1 |
Aliases | | ,HsT17379,MGC8664,SNX1A,Vps5, |
Gene summary | | This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This endosomal protein regulates the cell-surface expression of epidermal growth factor receptor. This protein also has a role in sorting protease-activated receptor-1 from early endosomes to lysosomes. This protein may form oligomeric complexes with family members. This gene results in three transcript variants encoding distinct isoforms. [provided by RefSeq] |
Location | | Chromosome: 15 Locus: 15q22.31 |
Gene position | | 64388177 - 64436433 Map Viewer |
Gene orientation | | plus |
Gene size | | 48257 bp |
Gene sequence |
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OMIM ID | | 601272 |
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