Entrez gene ID | | 6688 |
Official gene symbol | | SPI1 |
Full name | | spleen focus forming virus (SFFV) proviral integration oncogene spi1 |
Aliases | | ,OF,PU.1,SFPI1,SPI-1,SPI-A, |
Gene summary | | This gene encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors. The protein can also regulate alternative splicing of target genes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] |
Location | | Chromosome: 11 Locus: 11p11.2 |
Gene position | | 47400127 - 47376409 Map Viewer |
Gene orientation | | minus |
Gene size | | 23719 bp |
Gene sequence |
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OMIM ID | | 165170 |