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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for SPI1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID6688
Official gene symbolSPI1
Full namespleen focus forming virus (SFFV) proviral integration oncogene spi1
Aliases,OF,PU.1,SFPI1,SPI-1,SPI-A,
Gene summaryThis gene encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors. The protein can also regulate alternative splicing of target genes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
LocationChromosome: 11   Locus: 11p11.2
Gene position47400127 - 47376409  Map Viewer
Gene orientationminus
Gene size23719 bp
Gene sequence
OMIM ID165170