Entrez gene ID | | 6716 |
Official gene symbol | | SRD5A2 |
Full name | | steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) |
Aliases | | ,MGC138457, |
Gene summary | | This gene encodes a microsomal protein expressed at high levels in androgen-sensitive tissues such as the prostate. The encoded protein is active at acidic pH and is sensitive to the 4-azasteroid inhibitor finasteride. Deficiencies in this gene can result in male pseudohermaphroditism, specifically pseudovaginal perineoscrotal hypospadias (PPSH). [provided by RefSeq] |
Location | | Chromosome: 2 Locus: 2p23 |
Gene position | | 31806040 - 31749656 Map Viewer |
Gene orientation | | minus |
Gene size | | 56385 bp |
Gene sequence |
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OMIM ID | | 607306 |