Database of mammalian genes
Home

Home Search Browse RAGs User guide FAQs Links Questions Contribute

Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for BRAF (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID673
Official gene symbolBRAF
Full namev-raf murine sarcoma viral oncogene homolog B1
Aliases,B-RAF1,BRAF1,FLJ95109,MGC126806,MGC138284,RAFB1,
Gene summaryThis gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene. [provided by RefSeq]
LocationChromosome: 7   Locus: 7q34
Gene position140624564 - 140433812  Map Viewer
Gene orientationminus
Gene size190753 bp
Gene sequence
OMIM ID164757