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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for SSB (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID6741
Official gene symbolSSB
Full nameSjogren syndrome antigen B (autoantigen La)
Aliases,LARP3,La,
Gene summaryLa is involved in diverse aspects of RNA metabolism, including binding and protecting 3-prime UUU(OH) elements of newly RNA polymerase III (see MIM 606007)-transcribed RNA, processing 5-prime and 3-prime ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. La protein was originally defined by its reactivity with autoantibodies from patients with Sjogren syndrome (MIM 270150) and systemic lupus erythematosus (SLE; MIM 152700) (Teplova et al., 2006 [PubMed 16387655]).[supplied by OMIM]
LocationChromosome: 2   Locus: 2q31.1
Gene position170655389 - 170668575  Map Viewer
Gene orientationplus
Gene size13187 bp
Gene sequence
OMIM ID109090