Entrez gene ID | | 6775 |
Official gene symbol | | STAT4 |
Full name | | signal transducer and activator of transcription 4 |
Aliases | | ,SLEB11, |
Gene summary | | The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. [provided by RefSeq] |
Location | | Chromosome: 2 Locus: 2q32.2-q32.3 |
Gene position | | 192015925 - 191894306 Map Viewer |
Gene orientation | | minus |
Gene size | | 121620 bp |
Gene sequence |
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OMIM ID | | 600558 |