Entrez gene ID | | 6788 |
Official gene symbol | | STK3 |
Full name | | serine/threonine kinase 3 (STE20 homolog, yeast) |
Aliases | | ,FLJ90748,KRS1,MST2, |
Gene summary | | Protein kinase activation is a frequent response of cells to treatment with growth factors, chemicals, heat shock, or apoptosis-inducing agents. This protein kinase activation presumably allows cells to resist unfavorable environmental conditions. The yeast 'sterile 20' (Ste20) kinase acts upstream of the mitogen-activated protein kinase (MAPK) cascade that is activated under a variety of stress conditions. MST2 was identified as a kinase that is activated by the proapoptotic agents straurosporine and FAS ligand (MIM 134638) (Taylor et al., 1996 [PubMed 8816758]; Lee et al., 2001 [PubMed 11278283]).[supplied by OMIM] |
Location | | Chromosome: 8 Locus: 8q22.2 |
Gene position | | 99837909 - 99466861 Map Viewer |
Gene orientation | | minus |
Gene size | | 371049 bp |
Gene sequence |
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OMIM ID | | 605030 |
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