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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for STK3 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID6788
Official gene symbolSTK3
Full nameserine/threonine kinase 3 (STE20 homolog, yeast)
Aliases,FLJ90748,KRS1,MST2,
Gene summaryProtein kinase activation is a frequent response of cells to treatment with growth factors, chemicals, heat shock, or apoptosis-inducing agents. This protein kinase activation presumably allows cells to resist unfavorable environmental conditions. The yeast 'sterile 20' (Ste20) kinase acts upstream of the mitogen-activated protein kinase (MAPK) cascade that is activated under a variety of stress conditions. MST2 was identified as a kinase that is activated by the proapoptotic agents straurosporine and FAS ligand (MIM 134638) (Taylor et al., 1996 [PubMed 8816758]; Lee et al., 2001 [PubMed 11278283]).[supplied by OMIM]
LocationChromosome: 8   Locus: 8q22.2
Gene position99837909 - 99466861  Map Viewer
Gene orientationminus
Gene size371049 bp
Gene sequence
OMIM ID605030