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Gene information for TAF11 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID6882
Official gene symbolTAF11
Full nameTAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa
Aliases,MGC:15243,PRO2134,TAF2I,TAFII28,
Gene summaryInitiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a small subunit of TFIID that is present in all TFIID complexes and interacts with TBP. This subunit also interacts with another small subunit, TAF13, to form a heterodimer with a structure similar to the histone core structure. [provided by RefSeq]
LocationChromosome: 6   Locus: 6p21.31
Gene position34855819 - 34845555  Map Viewer
Gene orientationminus
Gene size10265 bp
Gene sequence
OMIM ID600772