Entrez gene ID | | 6888 |
Official gene symbol | | TALDO1 |
Full name | | transaldolase 1 |
Aliases | | ,TAL,TAL-H,TALDOR,TALH, |
Gene summary | | Transaldolase 1 is a key enzyme of the nonoxidative pentose phosphate pathway providing ribose-5-phosphate for nucleic acid synthesis and NADPH for lipid biosynthesis. This pathway can also maintain glutathione at a reduced state and thus protect sulfhydryl groups and cellular integrity from oxygen radicals. The functional gene of transaldolase 1 is located on chromosome 11 and a pseudogene is identified on chromosome 1 but there are conflicting map locations. The second and third exon of this gene were developed by insertion of a retrotransposable element. This gene is thought to be involved in multiple sclerosis. [provided by RefSeq] |
Location | | Chromosome: 11 Locus: 11p15.5-p15.4 |
Gene position | | 747432 - 765024 Map Viewer |
Gene orientation | | plus |
Gene size | | 17593 bp |
Gene sequence |
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OMIM ID | | 602063 |
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