Entrez gene ID | | 6905 |
Official gene symbol | | TBCE |
Full name | | tubulin folding cofactor E |
Aliases | | ,HRD,KCS,KCS1,pac2, |
Gene summary | | Cofactor E is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq] |
Location | | Chromosome: 1 Locus: 1q42.3 |
Gene position | | 235530728 - 235612280 Map Viewer |
Gene orientation | | plus |
Gene size | | 81553 bp |
Gene sequence |
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OMIM ID | | 604934 |
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