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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for TCF4 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID6925
Official gene symbolTCF4
Full nametranscription factor 4
Aliases,E2-2,ITF2,MGC149723,MGC149724,PTHS,SEF2,SEF2-1,SEF2-1A,SEF2-1B,bHLHb19,
Gene summaryThis gene encodes transcription factor 4, a basic helix-turn-helix transcription factor. The encoded protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers. This gene is expressed predominantly in pre-B-cells, although it is found in other tissues as well. Defects in this gene are a cause of Pitt-Hopkins syndrome. Multiple alternatively spliced transcript variants that encode different proteins have been described. [provided by RefSeq]
LocationChromosome: 18   Locus: 18q21.1
Gene position53255860 - 52889562  Map Viewer
Gene orientationminus
Gene size366299 bp
Gene sequence
OMIM ID602272