Database of mammalian genes
Home

Home Search Browse RAGs User guide FAQs Links Questions Contribute

Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for HNF1B (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID6928
Official gene symbolHNF1B
Full nameHNF1 homeobox B
Aliases,FJHN,HNF1beta,HNF2,HPC11,LF-B3,LFB3,MODY5,TCF2,VHNF1,
Gene summaryThis gene encodes a member of the homeodomain-containing superfamily of transcription factors. The protein binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha. The gene has been shown to function in nephron development, and regulates development of the embryonic pancreas. Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus, and expression of this gene is altered in some types of cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
LocationChromosome: 17   Locus: 17cen-q21.3
Gene position36105096 - 36046434  Map Viewer
Gene orientationminus
Gene size58663 bp
Gene sequence
OMIM ID189907