Entrez gene ID | | 6934 |
Official gene symbol | | TCF7L2 |
Full name | | transcription factor 7-like 2 (T-cell specific, HMG-box) |
Aliases | | ,TCF-4,TCF4, |
Gene summary | | This gene encodes a high mobility group (HMG) box-containing transcription factor that plays a key role in the Wnt signaling pathway. The protein has been implicated in blood glucose homeostasis. Genetic variants of this gene are associated with increased risk of type 2 diabetes. Several transcript variants encoding multiple different isoforms have been found for this gene. |
Location | | Chromosome: 10 Locus: 10q25.3 |
Gene position | | 114710009 - 114927437 Map Viewer |
Gene orientation | | plus |
Gene size | | 217429 bp |
Gene sequence |
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OMIM ID | | 602228 |