Entrez gene ID | | 6935 |
Official gene symbol | | ZEB1 |
Full name | | zinc finger E-box binding homeobox 1 |
Aliases | | ,AREB6,BZP,DELTAEF1,FECD6,MGC133261,NIL2A,TCF8,ZFHEP,ZFHX1A, |
Gene summary | | This gene encodes a zinc finger transcription factor. The encoded protein likely plays a role in transcriptional repression of interleukin 2. Mutations in this gene have been associated with posterior polymorphous corneal dystrophy-3 and late-onset Fuchs endothelial corneal dystrophy. Alternatively spliced transcript variants encoding different isoforms have been described. |
Location | | Chromosome: 10 Locus: 10p11.2 |
Gene position | | 31608101 - 31818742 Map Viewer |
Gene orientation | | plus |
Gene size | | 210642 bp |
Gene sequence |
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OMIM ID | | 189909 |
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