Entrez gene ID | | 701 |
Official gene symbol | | BUB1B |
Full name | | budding uninhibited by benzimidazoles 1 homolog beta (yeast) |
Aliases | | ,BUB1beta,BUBR1,Bub1A,MAD3L,SSK1,hBUBR1, |
Gene summary | | This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer. [provided by RefSeq] |
Location | | Chromosome: 15 Locus: 15q15 |
Gene position | | 40453210 - 40513337 Map Viewer |
Gene orientation | | plus |
Gene size | | 60128 bp |
Gene sequence |
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OMIM ID | | 602860 |