Entrez gene ID | | 7066 |
Official gene symbol | | THPO |
Full name | | thrombopoietin |
Aliases | | ,MGC163194,MGDF,MKCSF,ML,MPLLG,TPO, |
Gene summary | | Megakaryocytopoiesis is the cellular development process that leads to platelet production. The protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Alternate splicing results in multiple transcript variants of this gene. |
Location | | Chromosome: 3 Locus: 3q27 |
Gene position | | 184095932 - 184089773 Map Viewer |
Gene orientation | | minus |
Gene size | | 6160 bp |
Gene sequence |
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OMIM ID | | 600044 |
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