Database of mammalian genes
Home

Home Search Browse RAGs User guide FAQs Links Questions Contribute

Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for TLN1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID7094
Official gene symbolTLN1
Full nametalin 1
Aliases,ILWEQ,KIAA1027,TLN,
Gene summaryThis gene encodes a cytoskeletal protein that is concentrated in areas of cell-substratum and cell-cell contacts. The encoded protein plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. It codistributes with integrins in the cell surface membrane in order to assist in the attachment of adherent cells to extracellular matrices and of lymphocytes to other cells. The N-terminus of this protein contains elements for localization to cell-extracellular matrix junctions. The C-terminus contains binding sites for proteins such as beta-1-integrin, actin, and vinculin. [provided by RefSeq]
LocationChromosome: 9   Locus: 9p13
Gene position35732392 - 35697334  Map Viewer
Gene orientationminus
Gene size35059 bp
Gene sequence
OMIM ID186745